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Auteur Picard B |
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Xèmes Journées Annuelles de la Société française de Myologie (SFM) (14-16 novembre 2012; Grenoble (France)) ; Gueugneau M ; Coudy-Gandilhon C ; Meunier B ; Barboiron C ; Listrat A ; Féasson L ; Barthelemy JC ; Picard B ; Bechet D | Société Française de Myologie SFM | 2012Le vieillissement est associé à une perte musculaire et à l'apparition du syndrome métabolique (SM) qui est un facteur de risque pour les maladies cardiovasculaires. Cependant, les effets de ce syndrome sur le muscle squelettique des personnes â[...]Article
Delavaud A ; Gentes G ; Picard B ; Cassar-Malek I | 2011Myostatin (MSTN), a member of the TGF-_ family, is involved in muscle development and the maintenance of muscle mass homeostasis. We recently identified severalgenes and proteins, which are involved in the protection of cells against apoptosis t[...]Article
Delavaud A ; Gentes G ; Picard B | 2011In a previous study, we have identified the canonical Wnt signaling pathway as a putative target for inactivation of myostatin (MSTN) in mice. Here1 we have analysed the Mouse WNT signaling pathway in MSTN-null vs wild-type mice (n=5 animals/gro[...]Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Picard B ; Anne B ; Cassar-Malek I ; Chelh I ; Cottin P ; Gabillard JC ; Hadj Sassi A ; Leibovitch S ; Rodriguez J ; Seilliez I | AFM-TELETHON | 2011The control of muscle mass is determined by a dynamic balance of anabolic and catabolic processes. In the last decade, myostatin, a member of the TGFuperfamily, has emerged as a key factor in muscle growth regulation. The importance of myostatin[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Chelh I ; Meunier B ; Picard B ; Reecy J ; Chevalier C ; Hocquette JF ; Cassar-Malek I | 2008Myostatin (MSTN), a member of the TGF-beta superfamily, is a negative regulator of skeletal muscle mass. Inactivating mutations of the MSTN gene are responsible for the development of a hypermuscular phenotype in mice (McPherron et al., 1997) an[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Csibi A ; Lagirand-Cantaloube J ; Offner N ; Leibovitch MP ; Barboiron C ; Picard B ; Leibovitch S | 2008Skeletal muscle size depends upon a dynamic balance between anabolic and catabolic processes. The E3 ubiquitin-ligase MAFBx/Atrogin-1 is upregulated during muscle atrophy caused by a variety of conditions, including cancer, AIDS, stress, diabete[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Chaze T ; Meunier B ; Chambon C ; Jurie C ; Picard B | 2008Pre-natal period is crucial for muscle development in large species such as Bos taurus since the most part of differentiation process is completed at birth. Previous bovine studies displayed developmental stages representative of particular myog[...]